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Note that the IDPs/IDRs are fuzzy by default, as they exist as highly dynamic conformational ensembles

10.1152/ajpgi.00074.2006 121

The major cysteine catabolic pathway in humans occurs via the action of cysteine dioxygenase type 1 which oxidizes the sulfhydryl group of cysteine to sulfinate, producing the intermediate cysteine sulfinate

Carrying extra weight traps heat and makes hot flashes worse