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10.1358/dnp.2009.22.3.1325032 50 HallbergM

A significant decrease in arachidonate levels (20:4n-6) may be the cause of anti-inflammatory effects

As a long-acting IGF-1 analog, the compound represents a research subject in the broader field of peptide stability engineering specifically the use of structural modifications including N-terminal extension and amino acid substitution strategies to extend peptide half-life and modify peptide-binding protein interactions compared to native IGF-1 sequences