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Most patients notice appetite suppression within 3-7 days of starting a new GLP-1 medication, though full metabolic adjustment typically takes 2-4 weeks

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This research led to the development of two blockbuster weight-loss drugs: Wegovy by Novo Nordisk and Zepbound by Eli Lilly, now prescribed to millions as obesity affects 1 in 8 people globally

While nausea, vomiting, and diarrhea are class effects, their severity and clinical impact vary substantially across drugs