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While the inhibitory effects exerted by Ex4 on the HPG axis in some species might seemingly contradict its potential use of in humans, the role of more potent and longer lasting GLP-1 RA deserves further investigations
FDA approved Mounjaro for Type 2 Diabetes in 2022, and later for weight loss under the brand Zepbound in Nov 2023 (US)
Study Used AI to Analyze Real-World Patient Reports To better understand how people experience GLP-1 drugs outside of clinical trials, researchers used AI to analyze Reddit posts from 2019 to 2025
Medical disclaimer: GLP-1 therapy is prescribed only when clinically appropriate after a medical evaluation
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