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This intense inflammation is associated with damaging systemic events like oxidative stress, dysregulation of iron homeostasis, hypercoagulability and thrombus formation, acute respiratory distress syndrome, uncontrolled inflammation and organ failure (251257) (Figure 8)

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Rescue at the DNA Level Gene therapy encompasses techniques that can alter the expression of an organisms genes by targeting the DNA either through transgene delivery, or by direct modification of the genome, with the goal of therapeutically restoring a pathologically expressed gene to normal expression levels [38]

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury