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In conclusion, MNs/GLP-1RAs@NPs-WYRGRL could increase the expression of GLP-1R, inhibit the cGAS-STING signaling pathway, suppress ferroptosis in chondrocytes of articular cartilage, and promote the expression of chondrocyte-related mechanisms such as ACAN and COL2
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Treatment with the ghrelin-O-acyltransferase (GOAT) inhibitor GO-CoA-Tat reduces food intake by reducing meal frequency in rats
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