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Moreover, tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs) in the TME also contribute to ROS accumulation

In contrast to nociceptive pain, neuropathic pain is induced by a lesion or disease of the somatosensory nervous system that generates and maintains spontaneous pain and positive and negative sensory disturbances, independently from stimuli (Freynhagen et al., 2019