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The relative risk of congenital malformations between the group with statin use and the group with no statin use in the first trimester was 1.07 (95% confidence interval 0.85 to 1.37) after controlling for confounders, particularly pre-existing diabetes mellitus

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This is in agreement with the association of GPX4 with neuromelanin, as Lewy bodies have some association with neurons that have high neuromelanin content [3]

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