tirzepatide and memory problems on ingestive behavior in adults with overweight or obesity: a randomized 6-week phase 1 trial Tirzepatide (Zepbound) for weight loss

This 28-amino-acid peptide was originally isolated from the thymus gland, the very organ responsible for T cell maturation and immune tolerance

It is, however, necessary to continue further investigations to test the neuroprotective mechanisms of GLP-1 and GLP-1 RAs

Therefore, in T1DM, because of the lack of portal insulin levels, the liver stops producing enough IGF-1, which is followed by a compensatory rise in GH levels

Neurochemical parameters determination Calorimetric assay kits (Biodiagnostic Co., Egypt) were used to measure malondialdehyde (MDA), hydrogen peroxide (H 2 O 2 ), nitric oxide (NO), and glutathione reduced (GSH) in brain cortical tissue from all groups