can semaglutide cause constipation Ozempic constipation: How to treat it and prevent another bout How long after taking semaglutide

Theres evidence that these drugs affect the gut-brain axis, he adds, which might influence motility in more complex ways, but the main culprit is delayed gastric emptying. The gut-brain axis is the information superhighway between your gut and your brain

The programme spans multiple trials targeting distinct endpoints: On 21 May 2026 Eli Lilly reported topline results from TRIUMPH-1, the pivotal Phase 3 obesity trial and the programme's first Phase 3 efficacy readout: in 2,339 adults, mean weight loss at the 80-week primary endpoint reached 19.0% (4mg), 25.9% (9mg), and 28.3% (12mg) versus 2.2% for placebo (Eli Lilly investor release

Requires 1.5mL or 3mL syringe, or split into two injections

Not everyone in the first phase of the trial lost significant amounts of weight on the drug