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Specifically, it increases POMC and CART expression in the hypothalamus, the peptides that tell your brain you are full

Low protein consumption due to reduced appetite may also contribute to muscle loss and increased risk for sarcopenia, particularly among those with older age, perimenopausal or menopausal, lower testosterone, sedentary behavior, or lack of resistance/strength training [[63], [64], [65], [66]]

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A phase IIa active-comparator-controlled study to evaluate the efficacy and safety of Efinopegdutide in patients with non-alcoholic fatty liver disease