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APPROACHES TO USING ANTIOXIDANTS IN MEN There 3 main approaches that clinicians can use for antioxidants in managing male infertility: 1) Recommending antioxidants for all men with fertility issues 2) Reserve antioxidants for men who have certain significant risk factors (such as tobacco use or pyospermia) 3) Only use antioxidants if elevated levels of oxidative stress are found upon testing (as discussed above) None of these approaches has been proven superior at this point in time

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This effect was counteracted by knockdown of Usp2 , while Usp2 OE further intensified the fluorescence, indicating a heightened level of lipid oxidation