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It also marks this strategy as having high individual variability, tying the outcome to a person's baseline gut microbiota rather than to the fiber amount alone

140 OhJ

Therefore, tirzepatide represents a GLP-1R-biased agonist that shows less potency for -arrestin recruitment and activation of the GRK2 pathway, and consequently for receptor desensitization [126]

BENEFITS: Superior patient comfort for increased patient adherence