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This is illustrated in the figure at right

Lifestyle and Environmental Stress Glutathione is used by the body to fight off toxins, alcohol, and UV damage

FIGURE 9 Summary and conclusions: Glutathione and early (premature) inflammaging Chronic inflammatory diseases especially those compromising the lower respiratory system (chronic obstructive pulmonary disease, lower respiratory infections, cystic fibrosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome), diseases compromising the cardiovascular system (atherosclerosis, ischemic heart disease, stroke, and others), many other systemic inflammatory diseases like diabetes (274, 275)

Regulating the profibrogenic cytokine TGF-, which is found to be elevated in fibrotic Autoimmune diseases such as systemic sclerosis