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Effective vitamin B12 replacement should correct a macrocytic anaemia within 2 months and improve or correct neurological signs and symptoms within 6 months

Cost: SGLT2 medications are slightly less expensive than GLP-1 medications and range from $400-$800 per month without insurance or coupons

However, increasing evidence points towards other sites of action that might also have an important role, including the gastrointestinal tract, the gut microbial communities and the tissue-resident immune cells

Safety considerations and side effects No responsible discussion of peptide safety glosses over side effects