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GST polymorphisms are common in humans and range from frequencies as high as 20% to 60 % in some populations, including the null genotypes of GST Mu and Theta class (GSTM1 / and GSTT1 / , respectively), whereby individuals lack a catalytically active enzyme [74]

N Engl J Med 377:644657 Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde AM, Sabatine MS (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes

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