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Because the body's own production declines with age, illness, and stress, injection therapy is the most direct way to restore intracellular levels
The continuous production of ONOO could suppress the activity of glutathione reductase by nitration modification, thus collectively reducing detoxification and blocking DNA damage repair
This depletion correlates directly with elevated ventricular lactate levels, providing concrete biological evidence that the brains of these patients are trapped in a state of high oxidative stress and inefficient anaerobic metabolism
They even improve the skin's blood vessel microcirculation
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