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Metabolite identification The statistically significant features from each dataset were selected and annotated using Progenesis QI v.3.0 software (Waters Technologies, Milford, MA, USA)

ROS generation in spermatozoa Oxidative stress, and its role in the origins of male infertility was first appreciated in 1943, when the Scottish andrologist John MacLeod demonstrated that catalase could support the motility of human spermatozoa incubated under aerobic conditions [15]

These compounds are involved in various physiological activities