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The most commonly reported side effects include: Nausea Diarrhoea Vomiting Mild stomach discomfort Constipation In TRIUMPH-1, treatment discontinuation due to adverse events rose with dose: approximately 4.1% at 4 mg, 6.9% at 9 mg, and 11.3% at 12 mg , compared with 4.9% in the placebo group

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Following the therapy was a consistent counteraction of early and full multiorgan failure (and heart failure, in particular) and thrombosis of the described occlusion/occlusion-like syndrome [66,71,72,73,74,75,76,77,78,79,80,81,82], peripherally and centrally, and thereby, counteraction of the later isoprenaline-infarction and isoprenaline-reinfarction [79]

Certain groups are more likely to develop Vitamin B2 deficiency, including: Older adults, due to decreased nutrient absorption and limited food variety