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By geography, the segment is classified into five key regions: North America, Europe, Asia-Pacific, the Middle East and Africa, and Latin America

It is one of the most powerful endogenous antioxidants (produced by the body on its own)

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In fact, a specific cellular signaling pathway has been described in mice, including the activation of protease-activated receptor 2 and downstream enzymes phospholipase C and protein kinases A and C by mast cell triptase, and resultant sensitization of TRPV1, TRPV4, and TRPA1 (Chen et al., 2012) observed in vitro that paclitaxel administration induced oxidative stress byproducts which ultimately activate TRPA1 and TRPV4