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Global Ca 2+ genes define a signature for ferroptosis We speculated that changes in Ca 2+ homeostasis resulting in ferroptosis-resistant lipids may contribute to resistance in different cell lines

They also carry potential risks, including gastrointestinal side effects (nausea, bloating, vomiting), loss of lean muscle mass and sagging skin due to rapid weight loss, and more serious complications such as pancreatitis, thyroid conditions, and gallbladder disease. Additionally, most people gain the weight back after stopping the drugs which highlights the need for more sustainable, root-cause approaches to metabolic health and nutrition