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For example, combinations of GLP-1/glucagon RA achieve more liver fat content reduction in people with MASLD compared to GLP-1 RA alone despite similar WL, likely due to the direct effect of glucagon on hepatic lipid oxidation [79]

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These injections are not FDA-approved for weight loss and can cause side effects such as infection, scarring, and uneven skin texture

Common gastrointestinal side effects include: Nausea and vomiting Diarrhoea or constipation Abdominal pain and bloating Reduced appetite Indigestion These effects typically diminish as the body adjusts to the medication, usually within several weeks