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At the same time, SIRT1 deacetylates multiple transcription factors, such as Nrf2, promotes its entry into the nucleus and activates the expression of antioxidant stress genes, such as HO-1 and GPX4, the activation of which helps mitigate cell damage caused by ferroptosis

All study participants also received standard of care for their heart disease as recommended by their health care professional

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parapsilosis genes have the same or similar functions as orthologs in other yeast species, we noticed one major difference when we evaluated the ability of the mutant collection to synthesise amino acids, uracil and adenine (Supplementary Note 2 and Supplementary Fig