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Although the SAVOR and EXAMINE studies were delineated to verify cardiovascular safety of two DPP-4i, namely saxagliptin and alogliptin, respectively, both are considered to be the first controlled clinical trials to address the effect of GLP-1 system on CVD

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3 Takeaways from the Landmark Oral GLP-1 'Switch' Trial for Obesity Care The Weight Maintenance Challenge As clinicians on the front lines of obesity medicine, we are intimately familiar with the central challenge our patients face: sustaining weight loss after a period of initial success