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These GI effects are a class-wide phenomenon inherent to GLP-1 receptor agonism and are managed through gradual dose escalation starting at a low dose and increasing at defined intervals to allow gastrointestinal adaptation

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Int J Biol Macromol 101:502517 Tashakori-Miyanroudi M, Souresrafil A, Hashemi P, Ehsanzadeh SJ, Farrahizadeh M, Behroozi Z (2021) Prevalence of depression, anxiety, and psychological distress in patients with epilepsy during COVID-19: a systematic review