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These two groups thus differed only in the targeted delivery of Lani, but were otherwise matched by body weight and treated equally with GLP-1RGIPR co-agonist

[0027] In the present invention, a hydrazine solution is to be used in the removal of the Dde or ivDde protecting group, and there is a large potential safety hazard when a large amount of hydrazine is used in the scale-up production

In addition, GLP-1 treatments showed an improvement on left ventricular function as well as reducing the levels of the brain natriuretic peptide (BNP), which is a hormone associated with heart failure

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