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37 Poiteau L , Soulier A , Roudot-Thoraval F , Hzode C , Challine D , Pawlotsky JM , et al

JL: Funding acquisition, Writingoriginal draft

Enhancing mtDNA repair enzymes, POLG, which serves as the primary mtDNA polymerase, is essential for mtDNA replication and base excision repair of oxidative lesions [200]

We also discuss concussion, traumatic brain injury (TBI), Alzheimer's, and Parkinson's disease, and ways to restore or slow cognitive decline by using pharmacologic, lifestyle and behavioral protocols