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However, given the similar clinical efficacy and safety profiles amongst the available agents within the DPP-4 class of medications, the published head-to-head trials reviewed in this manuscript represent a good comparison of the two classes of medications ( Table 1 Changes in HbA1c, FPG, PPG, and weight from the randomized, head-to-head trials comparing GLP-1RA vs
There have been reports of some pharmacies, med spas, and online companies selling source ingredients that may subject patients to risk
Patients should not attempt to stop either medication abruptly without medical guidance, as phentermine cessation can cause fatigue and mood changes, while sudden semaglutide discontinuation may trigger rebound appetite and rapid weight regain
Why the dose schedule cannot be rushed Clinical trial data from the phase 2 NEJM study revealed something critical about dose scheduling
