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Genome-wide association studies have identified more than 260 single-nucleotide polymorphisms linked to AF pathogenesis, and genetic risk scores may enhance the accuracy of AF risk stratification (51, 52)

At the policy level, our analysis points out the necessity of improving access and funding for pediatric obesity pharmacotherapy to avoid further widening disparities

[PubMed: 16339487] 796

This dose-response relationship is remarkably consistent and was characterized in accompanying coverage as a robust Phase 3 signal for an oral preparation (HCPLive, 2025)