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GLP1/E improves metabolic and gonadal traits in a PCOS model of ovarian dysfunction We next assessed the metabolic, gonadal, and hormonal effects of the intervention with equivalent doses (10 nmol/kg) of GLP1, E, or GLP1/E in PNA mice, which retain ovulatory capacity albeit with clear dysregulation of ovarian cyclicity

The comparison is therefore not about which stimulates more GH, but about how much off-target endocrine activity a research design can tolerate

Endocrinology 149:20382047 [DOI] [PubMed] [Google Scholar] Jang HJ, Kokrashvili Z, Theodorakis MJ, Carlson OD, Kim BJ, Zhou J, Kim HH, Xu X, Chan SL, Juhaszova M, Bernier M, Mosinger B, Margolskee RF, Egan JM 2007 Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1