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The use of fertilizers containing Zn at low concentrations leads to the activation of antioxidant enzymes, non-oxidizing metabolism, as well as carbohydrate metabolism to reduce oxidative damage 54

It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile

Increasing the half-life of peptides is possible by preventing their degradation by blood proteases through blocking the C- and N-termini of peptides or forming cyclically shaped peptides [29]

BPC-157 (Body Protection Compound-157) is a 15-amino acid peptide derived from a protein found in gastric juice