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Selenium deficiency has been recognized as an environmental trigger for Hashimotos, and most people with Hashimotos are at risk for this deficiency, which can manifest as increased anxiety , fatigue , and depression

However, it also means that the dose-response relationship may change over time, possibly leading to dose escalation in tries to keep effects

Aspirin Acetaminophen (Tylenol) Antacids or laxatives Nirmatrelvir/ritonavir (Paxlovid) Certain antibiotics Antifungal drugs such as fluconazole (Diflucan) Ibuprofen (Advil) or naproxen sodium (Aleve) Atrial fibrillation medications such as amiodarone (Pacerone, Nexterone) Anti-seizure drugs, including phenytoin (Dilantin, Phenytek), phenobarbital (Sezaby), carbamazepine (Carbatrol, Tegretol, Equetro) 4

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