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Description

Second, Novo Nordisk has aggressively pursued label expansion, fully realizing semaglutide's therapeutic potential

MR: Conceptualization, Writing review & editing

Conversely, compounds with improved MC4R potency caused significant weight loss during their trials, including setmelanotide and, in some studies, bivamelagon (85, 90, 101)

The analysis focused on participants ages 12 to 35 years who achieved at least 10% weight loss while receiving injectable semaglutide