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(2016) reported that GHK-Cu increased collagen and elastin production by HDFa cells, depending on the mRNA expression of their TIMP (tissue inhibitor of metalloproteinases) over MMP (matrix metallopeptidase) [48]

In Adipoq / mice, P5 treatment can achieve similar effects

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The Teichman 2006 Phase II trial (N=65) established that CJC-1295 with DAC raises IGF-1 in healthy adults without serious adverse events at doses up to 60 mcg/kg [4]