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ClinicalTrials.gov identifier: NCT02166242

Box Content Medication Box Supplies for 28 days: 4 single-patient use EGRIFTA WR 11.6 mg vials (mix only 1 vial per week as per weekly mixing) Injection Box Supplies for 28 days: 1 multiple-dose, 30 mL bottle of Bacteriostatic Water for Injection (to be used for weekly mixing) 33 sterile BD SafetyGlide syringes with needle attached (orange cap), for daily injection 1 box of 100 alcohol swabs Figure A Weekly Mixing (Day 1) Getting Started For Weekly Mixing of EGRIFTA WR, follow steps 1 through 23

Therefore, POL is probably a weaker detergent type of sclerosing solution than STS, and higher concentrations are necessary to produce complete vascular sclerosis

The nasal route facilitates non-invasive administration, avoiding the need for injections or complex delivery systems, which may simplify protocol designs during experimental procedures