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Data from the same study also showed vitamin D3 reduced migraine-related disability scores and blood levels of CGRP during migraine attacks (Ghorbani 2020b)

As compared with nonobese HFpEF, patients with obesity-related HFpEF display distinct pathophysiologic features, including greater volume expansion 5,17 , more severe inflammation 6,7 , increases in visceral and paracardiac adipose tissue 5,15,18,19 and more severe myocardial injury 15

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Limitations of this approach, however, include the lack of quantitative analysis and of a structured assessment of the quality of studies and certainty of evidence, which were beyond the scope of this descriptive work