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The answer, sadly, isnt as simple as the question

Interestingly, filtered coffee was more likely to be linked to lower homocysteine than unfiltered coffee and, on average, approximately 150ml of coffee per day was more advantageous than higher consumption or no coffee consumption

HUBERMAN: So you can get really robust increases in growth hormone, but because there are ghrelin increases as well, you get big increases in hunger and anxiety in some people and lesser in others

Efficacy and safety of tirzepatide as novel treatment for type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials