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Cyclin D1 is a key protein in cell proliferation and initiates DNA synthesis (Figure 2A) by promoting the cell cycle (Figures 2B, C) and upregulating cyclin D1, CDK2, and CDK4 (Figure 2D)

Mahtani KR, Heneghan C, Onakpoya I, et al

In the following sections, we explain three major regenerative treatments being used clinically and review evidence of their effectiveness for EDS patients