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The fact that GHK-Cu not only stimulates the production of dermal components, but also regulates their breakdown suggests that it should be used with caution

[16] [17] [18] It was also established that GHK-Cu stimulates both the synthesis of metalloproteinases, the enzymes which break down dermal proteins, and their inhibitors (anti-proteases)

Changes in the intracellular redox environment of cells, through oxygen-derived free radical production known as oxidative stress, have been reported to be critical for cellular immune dysfunction, activation of apoptotic enzymes and apoptosis

Serotonin syndrome and other serotonergic disorders