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when damaged or absent, the conduction of nerve signals is slowed, causing numerous neurologic problems Neuron - a type of nerve cell that receives and transmits information within the brain and between the brain and the rest of the body Neurotransmitter - a chemical compound used by neurons to signal to each other Observational study - a human research study in which no experimental intervention or treatment is applied, and participants are simply observed over time Oxidative damage - damage that arises when the production of reactive oxygen species exceeds the ability of an organism to eliminate or neutralize them Placebo - a chemically inactive substance Plasticity - the ability to change Randomized controlled trial - a human research study in which participants are assigned by chance alone to receive either an experimental agent (the treatment group) or a placebo (the control group) Reactive oxygen species (ROS) - highly unstable oxygen-containing compounds that react easily with nearby cellular structures, potentially causing damage Synapse - sites of communication between neurons Synaptic plasticity - the capacity to change connections between neurons Test tube (in vitro) experiment - a research experiment performed in a test tube, culture dish, or other artificial environment outside of a living organism