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Regarding respiratory outcomes, while most findings were not statistically significant, GLP-1 RAs were associated with benefits in specific clinical scenarios, such as reducing the risk of pneumonia and improving outcomes in individuals with COVID-19, possibly mediated by anti-inflammatory mechanisms

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Semaglutide, a GLP-1 receptor agonist originally designed for type 2 diabetes, has demonstrated significant effects on lipid metabolism beyond weight reduction

Each of these substances belongs to a family called GLP-1 agonists