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The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

Recent multi-segmental magnetic resonance imaging study comparing patients with T2DM and healthy controls have found that patient T2DM group had 40% larger small bowel volume, less small bowel motility postprandially and there were positive associations between small bowel motility and constipation scores ( Conclusion This study identifies distinct expression patterns and functional effects of GLP-1 and GIP in jejunal muscle from obese individuals with and without T2DM

Roberfroid M, Gibson GR, Hoyles L, McCartney AL, Rastall R, Rowland I, Wolvers D, Watzl B, Szajewska H, Stahl B, Guarner F, Respondek F, Whelan K, Coxam V, Davicco MJ, Lotoing L, Wittrant Y, Delzenne NM, Cani PD, Neyrinck AM, Meheust A