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The large sample size (529 patients) also adds to its credibility, as it included participants across various demographics and regions, enhancing the generalizability of the findings

Dendritic cells (DCs), monocytes, and macrophages modulate the immune response by releasing a variety of proinflammatory cytokines, such as IL-1, IL-6, IL-8, and TNF, which influence the cellular and humoral response toward coronavirus infection and relate to its severity [24]

As such the only available proven effective therapeutic alternatives are psychosocial interventions, but their effects tend to be limited [45]

TB-500 (5 mg vials) TB-500 protocols often use higher doses, typically 2-2.5 mg twice weekly during loading phases