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This further leads to a reduction in liver glucose production

Pregnancy and lactation A retrospective observational study reported that daily oral supplementation with 600 mg of lipoic acid (racemic mixture) during pregnancy and without interruption from a period spanning between week 10 and week 30 of gestation and until the end of week 37 was not associated with any adverse effect in mothers and their newborns (114)

The low 1.5 mg dose is the starter dose for the Wegovy pill, which is made up of semaglutide, the same active ingredient found in its blockbuster injectable weight loss and diabetes treatments marketed under the brand names Wegovy and Ozempic

Oral supplements typically increase levels within one to two weeks, with normalisation taking three to six months depending on deficiency severity