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Pharmaceutics 15:452 Bojarska J, Mieczkowski A, Ziora ZM, Skwarczynski M, Toth I, Shalash AO, Parang K, El-Mowafi SA, Mohammed EH et al (2021) Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold
It stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the formation of new fat)
Patients with controlled uric acid level and doing well on allopurinol would seem to have no reason to switch to this new agent, in view of allopurinol's lower cost and 40-year history of an overall very good safety record (see "Allopurinol" discussion above)
Research Evidence The body of BPC-157 research consists primarily of preclinical animal studies, with very limited human clinical data
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