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Common and Systemic Side Effects Gastrointestinal Issues: The most common side effect of oral supplementation is mild, transient gastrointestinal (GI) discomfort, which can include mild bloating, cramping, loose stools, or general stomach upset

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Furthermore, peptides therapy would not be a chronic intervention, but these molecules would be administered only in a limited period of time during the 1st years of life of FXS children, when brain is still remodeling, to allow proper formation of the synaptic network

Although these changes did not reach statistical significance, they were accompanied by a twofold decrease in plasma leptin levels, consistent with fat mass reduction