CPTI Promotes Cancer Survival Under Metabolic Stress Numerous studies have shown that the overexpression of CPTI is tightly associated with tumor progression in breast cancer, 52, 53, 54 gastric cancer, 55 prostate cancer, 25, 50 lung cancer, 18 ovarian cancer, 56, 57 hepatoma, 58 myeloma 51 and high grade glioblastoma 29, 59 (roles of CPTI in various tumors are summarized in Table 1)
Convincing or probable evidence means there is strong research showing a causal relationship to cancereither decreasing or increasing the risk
e , SDS gels showing the different purification steps of recombinant FSP1 from bacterial cell lysates
In contrast, another substrate of DPP-4i, neuropeptide Y1-36 (NPY1-36), has shown potent vasoconstrictive effects