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FBW7, a substrate-recognition component of the SCF ubiquitin ligase complex, inhibits the transcription of SCD1 by antagonizing the transcription factor NR4A1, which subsequently decreases MUFA generation from SFAs and reverses resistance to ferroptosis

Aging 90 , 150.e155150.e111 (2020)

Somatotropic Pathway Interactions In specific research arrays, scientists evaluate how dsip affects the secretion of growth hormone

In EAT, it altered protein profile, increasing protective proteins like caveolin-1 (CAV1) and voltage-dependent anion-selective channel protein 3 (VDAC3), while reducing proinflammatory ones