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Description

Experimental design In order to generate the murine models of PCOS, C57BL6/J male and female mice were purchased from Charles River Laboratories (France)

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Suppressed glucagon release: It reduces the release of glucagon, a hormone from your liver that increases blood sugar levels

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NONCLINICAL TOXICOLOGY Carcinogenesis, Mutagenesis, Impairment of Fertility In a 2-year carcinogenicity study in CD-1 mice, subcutaneous doses of 0.3, 1, and 3 mg/kg/day (2-, 8-, and 22fold the maximum recommended human dose [MRHD] of 2.4 mg/week, based on AUC) were administered to the males, and 0.1, 0.3, and 1 mg/kg/day (0.6-, 2-, and 5-fold MRHD) were administered to the females

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