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Hrelec M, et al

When administered under medical supervision and according to recommended protocols, it is generally considered suitable for healthy adults

In parallel with analgesic tolerance, the ability of MOR to enhance [ 35 S]GTPS binding was reduced compared to naive animals (Bohn et al., 2000

serrata extract provided statistically substantial improvement in patients suffering osteoarthritis and was well-tolerated with minor gastric disturbance